Resident Evil 6 (RE 6): What Does the “Attack Reaction” Setting Do?

In Resident Evil 6, there is an option when you’re starting the game called Attack Reaction.

Since there’s no book with this game, and of course there’s no tool tip in the game either, how the hell do we know what this setting does?

Well I found out the good old fashioned way that this setting only turns on friendly fire.

So, you’ll probably want to leave this setting off, especially if you’re playing with randoms online.