During your missions in Africa, your team will come down with a random sickness. To prevent the disease from spreading you will have to quarantine some of your men to keep the others safe. This guide will help tell you Who To Quarantine In Metal Gear Solid 5.
Quick Edit – Not 100% sure it will always be the same language but the language is the common denominator here. Look through your infected list and see which language is used by all the sick people. Also, be careful when new recruits join, they could have the infected language without you knowing.
The disease only has an affect on males but the females can still spread it so put them in Quarantine as well. Even though they are away from everyone else, the guys in Quarantine can still die until you find a cure. You should avoid doing Side Ops and exploring until you figure out how to stop it. Focus on doing all story missions until you get it sorted out. I ended up with 260+ soldiers in Quarantine by the end of this and lost about 70 of my best men.
Ride like the wind if you want to save as many as you can!
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