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Plague Inc – How to Beat Nano Virus on Brutal

Beating Nano Virus on Brutal is fairly similar to beating it on Normal, but you have to be a little more aggressive because the cure builds a bit quicker.

You’ll need to invest in just about every ability that reduces the cure. Don’t get too alarmed when the cure begins to rise right from the start, you’ll be able to slow it down enough in the end to win.

Gene Setup for Nano Virus on Brutal

DNA Gene: Metabolic Jump
Travel Gene: Aquacyte
Evolution Gene: Patho-Stasis
Mutation Gene: Genetic Mimic
Environment Gene: Extremophile

Starting your Nano Virus

Start in China since it’s the largest country and has general benefits to all climates.

You’re going to start fighting the cure immediately, since the kill switch starts being built before the world is even aware of your plague.

Purchase Code Fragment Interception and Radical Elements Stabilized on the Abilities page right as soon as you have points for them. Next purchase Code Segment Interception and Encryption Breached on Abilities as well. This will slow the kill switch work quite a bit.

Now that you have a little cushion, you can start spreading more. Purchase Air 1 and Water on Transmissions when you have enough points.

Next buy these symptoms: Nausea, Coughing, Rash, Anaemia, Cysts, Hypersensitivity, Paralysis, Coma as soon as you can. If Total Organ Failure ever mutates before everyone is infected, devolve it immediately.

Take down some of the resistances by purchasing Drug Resistance 1 and Cold Resistance 1, Heat Resistance 1, and then Genetic Hardening 1 and 2 here as well to slow down the kill switch some more.

When you’ve spread some more and banked a few more points, purchase Air 2, Water 2, and Extreme Bioaerosol under Transmissions.

You should be making some good progress at this point, and a lot of points. The cure will keep rising, but don’t panic yet because you should still have time. The end moves pretty quickly once the planet is infected.

Load up on some more infectious symptoms like Sneezing, Pneumonia, Sneezing, Sweating, Haemophilia, and Abscesses.

A ton of points should be rolling in right about now. Purchase Drug Immunity, Drug Resistance 2, Cold Resistance 2, and all of the Genetic Reshuffles under Abilities.

If you have any closed land borders that need to be infected at this point, you can purchase Bird 1 & 2 to help infect them. This is when I like to unleash Replication Factory Overload under Abilities to give your plague a huge boost in infectivity for a short period, but the side effect will be a reduction in Infectivity in the long run, which is fine because we’re about done spreading anyway. After you purchase Replication Factory Overload, you can purchase Drug Immunity as well to increase infectivity back up in wealthy countries.

FINISH THEM!

Once everyone in the planet is infected, it’s time to unleash hell!

Purchase Total Organ Failure, and any other deadly symptom you can afford. The more people die, the slower the cure will build and the more points you’ll receive to purchase more deadly symptoms. Don’t let up, and keep throwing whatever you can at them.

If the cure builds close to 100 during this process (it shouldn’t, but just in case) purchase Broadcast Interceptor Overload, which stops the cure entirely for several weeks. This should give you enough time to kill off enough people to slow it entirely.

Congrats, you win!

Plague Inc. - Nano Virus on Brutal

Having troubles, or have suggestions or builds of your own? Leave me a comment below and let me know.