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Can 2 people play xbox 360

Can 2 people play xbox 360
It depends upon the game you are trying to play. If it is compatible for two players (or more) then yes, all you need is two controllers.

Some examples would be Halo 3 and Call of Duty 4
If it is not compatible for two players, then no, you cannot.
Some examples would be Halo Wars and Fracture